Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
€818.00
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From €140.00 €119.00
Inhibition of cardiac late sodium current (late INa) is a strategy to suppress arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure. GS967 is a selective inhibitor of late INa that has been shown to suppress experimentally induced arrhythmias in rabbit myocytes and hearts.{30900} It can inhibit A. sulcata toxin II–induced late INa in ventricular myocytes and isolated hearts with IC50 values of 0.13 and 0.21 µM, respectively.{30900} GS967 causes minimal inhibition of the delayed-rectifier potassium current nor does it affect L- or T-type calcium channel currents, sodium-calcium exchanger currents, or a panel of 162 receptors, ion channels, transporters, and enzymes.{30900}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg, 25 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 1262618-39-2 |
| Molecular formula | C14H7F6N3O |
| Smiles | FC(OC1=CC=C(C(C=C2)=CN3C2=NN=C3C(F)(F)F)C=C1)(F)F |
| Molecular weight | 347,2 |
| Custom code | 2933.49 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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