Gramicidin

CAT N°: 28251
Price:

322.00 273.70

Gramicidin is a polypeptide antibiotic mixture of gramicidin A (Item No. 26384), gramicidin B, and gramicidin C originally isolated from B. brevis.{47490} It is also a component of the antibiotic tyrothricin (Item No. 22177).{47491} Gramicidin is active against the Gram-positive bacterium S. aureus but not Gram-negative E. coli.{38058} It also protects mice from Pneumococcus infection in vivo when administered at a dose of 0.002 mg/animal. Gramicidin inhibits growth of bacteria by forming pores and channels in the cell wall, which increases its permeability to monovalent cations.{47490} Formulations containing gramicidin have been used as topical agents in the treatment of bacterial skin infections.

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