Glucose-6-Phosphate Dehydrogenase Activity Assay Kit

Territorial Availability: Available through Bertin Technologies only in France

• Correlated keywords
  • kits assays measures measurements Glucose 6 six phosphates Glucose-6-phosphates dehydrogenases cytosolic enzymes catalyzes pentose pathway ribose-5-phosphates precursor RNA ribonucleic acids DNA deoxyribonucleic ATP adenosine triphosphates CoA coenzymes A NAD nicotinamides adenine dinucleotides FAD flavin NADPH phosphates energy cells fatty oxidations lipids biosynthesis substrates oxidases macrophages polymorphonuclear leukocytes oxygen radicals pathogens intracellular metabolic de novo amino red blood RBC mitochondria pentose oxidative damage stress hemolytic anemia neonatal hyperbilirubinemia acute hemolysis chronic X-linked sex-linked hereditary genetics defect mutations G6PD genes malaria Plasmodium falciparum upregulated rat mouse murine obesity hyperglycemia hyperinsulinemia mediator insulin resistance post-translationally preneoplastic lesions tumors suppressors p53 human dimers fluorescence-based erythrocytes lysates tissues homogenates cultures samples 6-phospho-D-gluconate fluorometrics fluorescent
• Product Overview:
  Glucose-6-phosphate dehydrogenase (G6PDH) is a cytosolic enzyme that catalyzes the first step in the pentose phosphate pathway. This pathway includes converting glucose to ribose-5-phosphate, a precursor to RNA, DNA, ATP, CoA, NAD, and FAD. The pathway also generates NADPH. G6PDH deficiency, the most common enzyme deficiency worldwide, causes a spectrum of diseases including neonatal hyperbilirubinemia, acute hemolysis, and chronic hemolysis. G6PDH activity has been shown to be upregulated in rat and mouse models of obesity, hyperglycemia, and hyperinsulinemia. Cayman’s Glucose-6-Phosphate Dehydrogenase Assay provides a fluorescence-based method for detecting G6PDH activity in a variety of samples including erythrocyte lysates, tissue homogenates, and cell culture samples.