Glp-Amyloid-? (3-40) Peptide (human) (trifluoro<wbr/>acetate salt)

Glp-Amyloid-? (3-40) Peptide (human) (trifluoroacetate salt)

CAT N°: 27416
Price:

1,237.00 1,051.45

Glp-Amyloid-? (3-40) peptide is a fragment of amyloid-? (1-40) (A?40; Item No. 21617) that contains the cyclic amino acid pyroglutamate at the N-terminus. Glp-Amyloid-? (3-40) peptide is a major component of the endogenous amyloid-? content in post-mortem brain tissue from patients with Alzheimer’s disease.{50304} It is formed through cleavage of the N-terminal aspartate and alanine on A?40 and A?42 followed by dehydration of glutamic acid by glutaminyl cyclase.{50305} Glp-Amyloid-? (3-40) peptide has been used as a reference peptide for the quantification of total pyroglutamate amyloid-? in APP23 mouse brain.{50304}

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