GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoro<wbr/>acetate salt)

GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt)

CAT N°: 24887
Price:

276.00 234.60

Glucagon-like peptide 1 (GLP-1) (7-37) is an endogenous incretin hormone and truncated form of GLP-1 (1-37) (Item No. 24460) that is produced via cleavage of preproglucagon in the pancreas and intestine.{38949} It binds to ?TC-1 and RIN 1027-B2 cells (Kds = 3.3 and 3.5 nM, respectively) and enhances insulin secretion in ?TC-1 cells in a concentration- and glucose-dependent manner.{38950} Ex vivo, GLP-1 (7-37) stimulates insulin release from perfused rat pancreas.{38949} GLP-1 (7-37) increases plasma insulin concentrations by greater than 50% as compared to vehicle control in response to hyperglycemia in rats when administered at a dose of 15 pmol/min/kg for five days.{38951}

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