Gliovirin

Gliovirin

CAT N°: 28583
Price:

818.00 695.30

Gliovirin is a fungal metabolite that has been found in T. harzianum and has fungicidal, antimicrobial and anti-inflammatory activities.{46408} It is active against the plant pathogenic fungus P. ultimum (MIC = 60 ng/ml) and the parasite T. brucei brucei (IC50 = 90 ng/ml), but has no effect on the plant pathogenic fungi R. solani, P. omnivorum, T. basicola, R. arrhizus, and V. dahliae or the bacteria B. thuringiensis, P. fluorescens, and X. malvacearum when used at concentrations up to 1,000 ng/ml.{46409,46410} Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50 = 1 µM) and protein levels of IL-2 in Jurkat cells (IC50 = 5.2 µM).{46408}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (1aS,4R,4aS,8S,9R,11aR,12aS)-4,4a,8,9-tetrahydro-4-hydroxy-9-(2-hydroxy-3,4-dimethoxyphenyl)-12H-8,11a-(iminomethano)-1aH,7H-[1,2,4]dithiazepino[4,3-b]oxireno[e][1,2]benzoxazine-7,13-dione
  • Correlated keywords
    • Trichoderma microbial antiinflammatory Pythium Trypanosoma Rhizoctonia Phymatotrichopsis Thielaviopsis Rhizopus Verticillium Bacillus Bt Pseudomonas Xanthomonas COX2 IL2 interleukin
  • Product Overview:
    Gliovirin is a fungal metabolite that has been found in T. harzianum and has fungicidal, antimicrobial and anti-inflammatory activities.{46408} It is active against the plant pathogenic fungus P. ultimum (MIC = 60 ng/ml) and the parasite T. brucei brucei (IC50 = 90 ng/ml), but has no effect on the plant pathogenic fungi R. solani, P. omnivorum, T. basicola, R. arrhizus, and V. dahliae or the bacteria B. thuringiensis, P. fluorescens, and X. malvacearum when used at concentrations up to 1,000 ng/ml.{46409,46410} Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50 = 1 µM) and protein levels of IL-2 in Jurkat cells (IC50 = 5.2 µM).{46408}

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