Ginkgolide B

Ginkgolide B

CAT N°: 14636
Price:

From 48.00 40.80

Platelet-activating factor (PAF) is an important mediator of cell proliferation, angiogenesis, inflammatory response regulation, vasodilation, superoxide formation, and platelet aggregation.{939} These cellular effects are mediated through its specific G-protein coupled receptor, PAFR.{12279} Ginkgolide B, a terpenoid extracted from G. biloba leaves, is a potent PAFR antagonist that inhibits platelet aggregation at concentrations from 10-500 ?M.{23210} It has been shown to inhibit non-mucinous ovarian cancer proliferation by blocking cell cycling.{16867} Ginkgolide B also demonstrates number of other anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects.{23211}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3’,2’:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione
  • Correlated keywords
    • 99796-69-7 BN 52021 BN52021 BN-52021 52051 BN52051 BN-52051 platelets-activating platelets activating actives activates factors receptors PAFs aggregations PAFR antagonists anticancer anti-cancer anti cancers inflammatory antiinflammatory allergic anti-allergic oxidants anti-oxidant anti-inflammatory anti-allergic antioxidants neuroprotectives ginkgolide-b terpenoids ginkgo biloba g. leaves ovarian mucinous bilobalide mediators cells proliferations angiogenesis responses regulations vasodilations superoxides formations G-protein Gs proteins coupled receptors tranduces signals phosphorylations cascades ginkgolide Bs inhibits inhibiting inhibitions inhibitors extracted cancers blocking cycling
  • Product Overview:
    Platelet-activating factor (PAF) is an important mediator of cell proliferation, angiogenesis, inflammatory response regulation, vasodilation, superoxide formation, and platelet aggregation.{939} These cellular effects are mediated through its specific G-protein coupled receptor, PAFR.{12279} Ginkgolide B, a terpenoid extracted from G. biloba leaves, is a potent PAFR antagonist that inhibits platelet aggregation at concentrations from 10-500 ?M.{23210} It has been shown to inhibit non-mucinous ovarian cancer proliferation by blocking cell cycling.{16867} Ginkgolide B also demonstrates number of other anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects.{23211}

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