Gilvocarcin M

Gilvocarcin M

CAT N°: 25762
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507.00 430.95

Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus.{22205} It is active against S. aureus when used at a concentration of 32 µg/ml.{43405} Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 µg/ml) but has no effect on survival in a P388 mouse model of leukemia when used at doses ranging from 25 to 400 mg/kg.{22206} Gilvocarcin M intercalates into bacteriophage PM2 DNA.{43406} It is toxic to rats with an intravenous LD50 value of 450 mg/kg.{22206}

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