Ganodermanontriol

Ganodermanontriol

CAT N°: 34325
Price:

From 365.00 310.25

Ganodermanontriol is a triterpene that has been found in G. lucidum and has diverse biological activities.{62271,62272,62273,62274} It inhibits the activity of HIV-1 protease (IC50 = 70 µM), as well as reduces the activity of 5?-reductase by 32% when used at a concentration of 667 µM.{62271,62272} Ganodermanontriol (25 and 50 µM) inhibits proliferation, colony formation, invasion, and migration of MDA-MB-231 human breast cancer cells.{62273} It reduces hepatocyte necrosis and increases in hepatic TNF-? and IL-6 levels in a mouse model of LPS/D-galactosamine-induced acute liver injury when administered at a dose of 5 mg/kg.{62274}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 24S,25R,26-trihydroxy-lanosta-7,9(11)-dien-3-one
  • Correlated keywords
    • 1192133-46-2 Ganoderma HIV1 MDAMB231 MDAMB IL6
  • Product Overview:
    Ganodermanontriol is a triterpene that has been found in G. lucidum and has diverse biological activities.{62271,62272,62273,62274} It inhibits the activity of HIV-1 protease (IC50 = 70 µM), as well as reduces the activity of 5?-reductase by 32% when used at a concentration of 667 µM.{62271,62272} Ganodermanontriol (25 and 50 µM) inhibits proliferation, colony formation, invasion, and migration of MDA-MB-231 human breast cancer cells.{62273} It reduces hepatocyte necrosis and increases in hepatic TNF-? and IL-6 levels in a mouse model of LPS/D-galactosamine-induced acute liver injury when administered at a dose of 5 mg/kg.{62274}

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