(–)-Gallocatechin

(–)-Gallocatechin

CAT N°: 16944
Price:

From €55.00 €46.75

(?)-Gallocatechin ((?)-GC) is an epimer of (?)-epigallocatechin ((?)-EGC; Item No. 11809). They are flavan-3-ols and members of the catechin family of polyphenolic antioxidants found in green tea and other plant extracts.{23119} Both (?)-GC and (?)-EGC are potent antioxidants and significantly inhibit the proliferation of HCT116 and SW480 cancer cells.{23115,27615,23119} (?)-GC also inhibits the aggregation of amyloid ? peptide in vitro (IC50 = 17.5 µM).{27617} With increasing temperature, the steaming of green tea leaves results in the reduction of 2,3-cis isomers, like (?)-EGC, and an increase in 2,3-trans isomers, like (?)-GC.{27615,27616}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (2S,3R)-3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol
  • Correlated keywords
    • biochemical natural product antioxidant inflammation cancer inhibitor Alzheimer’s research inhibit flavonoid flavan-3-ol catechin family polyphenolic green tea plant extract epimer (-)-epigallocatechin EGC proliferation HCT-116 HCT116 SW-480 SW480 cell aggregation amyloid ? peptide in vitro increase temperature steaming leaves reduction reduce 2,3-cis isomers 2,3-trans (-)-Gallocatechol l-Gallocatechin
  • Product Overview:
    (?)-Gallocatechin ((?)-GC) is an epimer of (?)-epigallocatechin ((?)-EGC; Item No. 11809). They are flavan-3-ols and members of the catechin family of polyphenolic antioxidants found in green tea and other plant extracts.{23119} Both (?)-GC and (?)-EGC are potent antioxidants and significantly inhibit the proliferation of HCT116 and SW480 cancer cells.{23115,27615,23119} (?)-GC also inhibits the aggregation of amyloid ? peptide in vitro (IC50 = 17.5 µM).{27617} With increasing temperature, the steaming of green tea leaves results in the reduction of 2,3-cis isomers, like (?)-EGC, and an increase in 2,3-trans isomers, like (?)-GC.{27615,27616}

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