Gallamine (iodide)

Gallamine (iodide)

CAT N°: 26086
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From 74.00 62.90

Gallamine is an allosteric modulator of muscarinic acetylcholine receptors.{45058} It slows the dissociation of the muscarinic antagonist [3H]NMS from M1-M5 muscarinic receptors, with the highest potency for M2 receptors. Gallamine is cardioselective, inhibiting [3H]NMS binding in rat heart tissue homogenates more potently than in other tissues (IC50s = 0.8 and 3-30 µM, respectively).{45059} Formulations containing gallamine have previously been used as neuromuscular blockers during surgery.

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