€474.00 €402.90
The prostaglandin F2? receptor (FP receptor) is a G protein-coupled receptor known to elicit smooth muscle contraction in a variety of tissues.{9114} FP receptor mRNA is found in reproductive, gastric, neural, and ocular tissues as well as specialized cells of the kidney.{3160,1374,1680,9666} Two FP receptor isoforms, FPA and FPB have been identified in sheep.{3905} FPB receptor is truncated at the carboxy-terminus thereby preventing desensitization (which normally occurs by protein kinase C phosphorylation of FPA) and produces aberrant signalling in FPB transfectants.{7614,9285} The existence of a truncated human FP isoform responsible for signal-amplification contributing to luteolysis, cell growth, or malignant transformation is currently unknown.{3905,7614,9285,4688} Cayman’s FP Receptor Polyclonal Antibody can be used for Western blot applications. The calculated size of FP Receptor is 41 kDa and this antibody recognizes multiple bands from 50-67 kDa from human, bovine, mouse, ovine, and rat samples.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 ea |
|---|---|
| Shipping | dry ice |
| Molecular weight | 0 |
| Host | Rabbit |
| Antigen | Synthetic peptide from the N-terminal cytoplasmic region of mouse protein FP receptor |
| Isotype | IgG |
| Application(s) | WB |
| Formulation | Peptide-affinity purified antibody lyophilized from 500 µl |
| Custom code | 3822.19 |
| UNSPSC code | 12352203 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.
Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009
Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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