Folipastatin

Folipastatin

CAT N°: 24924
Price:

From 237.00 201.45

Folipastatin is a fungal metabolite produced by A. unguis and an inhibitor of phospholipase A2 (PLA2; IC50 = 39 ?M).{38997} It inhibits release of arachidonic acid (Item Nos. 90010 | 10006607) from rat polymorphonuclear leukocytes (IC50 = 24 ?M). Folipistatin also inhibits radioligand binding to L-type calcium channels in porcine heart membranes (IC50 = 0.39 ?M) but has no effect on contraction of taenia (IC50 = >100 ?M).

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3,8-dihydroxy-4,9-dimethyl-1,6-bis[(1Z)-1-methyl-1-propen-1-yl]-11H-dibenzo[b,e][1,4]dioxepin-11-one
  • Correlated keywords
    • PLA-2 Aspergillus PL-A2
  • Product Overview:
    Folipastatin is a fungal metabolite produced by A. unguis and an inhibitor of phospholipase A2 (PLA2; IC50 = 39 ?M).{38997} It inhibits release of arachidonic acid (Item Nos. 90010 | 10006607) from rat polymorphonuclear leukocytes (IC50 = 24 ?M). Folipistatin also inhibits radioligand binding to L-type calcium channels in porcine heart membranes (IC50 = 0.39 ?M) but has no effect on contraction of taenia (IC50 = >100 ?M).

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