Florfenicol-d<sub>3</sub>

Florfenicol-d3

CAT N°: 28538
Price:

524.00 445.40

Florfenicol-d3 is intended for use as an internal standard for the quantification of florfenicol (Item No. 19458) by GC- or LC-MS. Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Item No. 21357).{53126} It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml).{53127} Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml).{53128} It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM.{53126} Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methyl-d3-sulfonyl)phenyl]ethyl]-acetamide
  • Correlated keywords
    • deuterated deuterium SCH25298 SCH-25298 ant-ibiotic
  • Product Overview:
    Florfenicol-d3 is intended for use as an internal standard for the quantification of florfenicol (Item No. 19458) by GC- or LC-MS. Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Item No. 21357).{53126} It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml).{53127} Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 µg/ml).{53128} It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM.{53126} Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.

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