Fisetin

Fisetin

CAT N°: 15246
Price:

From 48.00 40.80

Fisetin is a flavonoid that has been found in various fruits and vegetables and has diverse biological activities.{61545,61546,61547,61548} It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay and inhibits oxidative burst induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP; Item No. 21495) in isolated human polymorphonuclear neutrophils (PMNs) when used at a concentration of 10 µM.{61545,61547} Fisetin (10-60 µM) induces cell cycle arrest at the G1 phase and apoptosis in, as well as inhibits the proliferation of, LNCaP prostate cancer cells.{61546} It inhibits LPS-induced production of nitrite, prostaglandin E2 (PGE2; Item No. 14010), and NF-?B activation in RAW 264.7 cells.{61547} Fisetin (1 mg/animal) reduces tumor growth in a CWR22R?1 prostate cancer mouse xenograft model.{61548}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
  • Correlated keywords
    • biochemical natural product antioxidant inhibitor cancer oxidative injury intracellular signaling signal transduction flavonoid inflammation inhibit flavonol anti-inflammatory activator sirtuin 1 SIRT1 spleen tyrosine kinase SYK suppressor CD36 gene expression 3,3′,4′,7-tetrahydroxyflavone 5-Desoxyquercetin Bois Bleu de Honqrie C.I. 75620 C.I.75620 CI Natural Brown 1 Cotinin Fiestin Fietin Fisetholz Fisitin Fustel Fustet Junger Fustik LDN 0058389 LDN0058389 Superfustel K Ungarisches Gelbholz Ventin Sumach Viset Young Fustic Crystals Zante
  • Product Overview:
    Fisetin is a flavonoid that has been found in various fruits and vegetables and has diverse biological activities.{61545,61546,61547,61548} It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay and inhibits oxidative burst induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP; Item No. 21495) in isolated human polymorphonuclear neutrophils (PMNs) when used at a concentration of 10 µM.{61545,61547} Fisetin (10-60 µM) induces cell cycle arrest at the G1 phase and apoptosis in, as well as inhibits the proliferation of, LNCaP prostate cancer cells.{61546} It inhibits LPS-induced production of nitrite, prostaglandin E2 (PGE2; Item No. 14010), and NF-?B activation in RAW 264.7 cells.{61547} Fisetin (1 mg/animal) reduces tumor growth in a CWR22R?1 prostate cancer mouse xenograft model.{61548}

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