Fenbufen

Fenbufen

CAT N°: 28851
Price:

48.00 40.80

Fenbufen is a non-steroidal anti-inflammatory drug (NSAID) and a prodrug form of 4-biphenylacetic acid.{52083} Fenbufen (125 ?g/ml) inhibits collagen-induced, but not arachidonate-induced, platelet aggregation in vitro.{52084} In vivo, fenbufen (8-250 mg/kg) suppresses UV-induced erythema in guinea pigs.{52083} It reduces phenylquinone-induced writhing in mice (ED50 = 7.7 mg/kg) and brewer’s yeast-induced mechano-allodynia in rats (ED50 = 29 mg/kg).{52084} Fenbufen (28 mg/kg) reduces inflammation in a rat model of adjuvant-induced arthritis. It also reduces yeast-induced fever in rats. Formulations containing fenbufen were previously used in the treatment of osteoarthritis and inflammatory pain.

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