Extracellular Death Factor

Extracellular Death Factor

CAT N°: 15478
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100.00 85.00

Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells.{24994} It is sensitive to extreme pH, high temperatures, and other stressful conditions.{24994} At 2.5 ng/ml, EDF has been shown to facilitate mazEF-mediated cell death, significantly reducing population size in E. coli cultures.{24994}

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