Ethynyl Estradiol

Ethynyl Estradiol

CAT N°: 10006486
Price:

48.00 40.80

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.{9611} Ethynyl estradiol is a synthetic analog of 17?-estradiol (Item No. 10006315). A USP-approved grade of ethynyl estradiol is often formulated in combination with a progestin such as norgestrel (Item No. 10006319)/levonorgestrel (Item No. 10006318) or desogestrel and provided for use as an oral contraceptive. Efficacy of oral administration of ethynyl estradiol is facilitated by the ethynyl substitution at the C-17 position, which inhibits first pass hepatic metabolism. Ethynyl estradiol is also rapidly and almost completely absorbed from the gastrointestinal tract.{12906}

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