Ethotoin

Ethotoin

CAT N°: 24022
Price:

From 92.00 78.20

Ethotoin is a hydantoin anticonvulsant.{37306,37305} It shortens the duration of the tonic extensor aspect of seizures induced by maximal electroshock in rats when administered at doses ranging from 500-1,000 mg/kg.{37305} It also decreases the duration of the tonic phase of seizures at a dose of 1,000 mg/kg but does not affect the duration of the clonic phase at any dose.{37305} Ethotoin (20 mg/kg, i.p.) decreases serum cholesterol and triglyceride concentrations in mice to 67 and 60%, respectively, of control after 16 days of treatment.{37307} Formulations containing ethotoin have been used in the treatment of tonic-clonic and complex partial seizures.

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