Estradiol 3-<wbr/>(?-<wbr/>D-<wbr/>Glucuronide) (sodium salt)

Estradiol 3-(?-D-Glucuronide) (sodium salt)

CAT N°: 16155
Price:

From 102.00 86.70

Estradiol 3-(?-D-glucuronide) (E23G) is a non-cholestatic regioisomer of the estrogen metabolite, estradiol 17-(?-D-glucuronide) (E217G; Item No. 16156).{26342,26341} It acts as a substrate for multidrug resistance protein 2 (MRP2; Km = 122 µM), competing with E217G for MRP2-mediated transport (IC50 = 14.2 µM).{26341,26340} E23G has been reported to inhibit E217G transport through rat organic anion-transporting polypeptide 1 with a Ki value of 9.7 µM, but is a low-affinity inhibitor of both MRP4 and MRP7 (IC50s = ~ 100 µM).{26341}

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