Erythro<wbr/>mycin A N-oxide

Erythromycin A N-oxide

CAT N°: 23642
Price:

165.00 140.25

Erythromycin A N-oxide is a potential impurity found in commercial preparations of erythromycin.{35178} Erythromycin (Item No. 16486) is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains.{22680} It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l).{22758} Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications.{22760,17924} Erythromycin A N-oxide is also a precursor in the synthesis of clarithromycin (Item No. 19455).{35220}

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