Erianin

Erianin

CAT N°: 32516
Price:

From 48.00 40.80

Erianin is a benzoyl compound that has been found in D. chrysotoxum and has diverse biological activities.{57436,57437,57438} It inhibits the growth of H460 and H1299 lung cancer cells in a calcium/calmodulin-dependent manner, an effect that can be reversed by the ferroptosis inhibitor liproxstatin-1 (Item No. 17730) or ferrostatin-1 (Item No. 17729).{57436} Erianin (100 mg/kg) reduces tumor volume in an H460 mouse xenograft model. It increases colon length and body weight, as well as decreases colonic inflammation and the number of colonic ulcers in a mouse model of ulcerative colitis induced by dextran sulfate (DSS; Item No. 23250).{57437} Erianin (10 mg/kg) decreases retinal microglia accumulation, NF-kB signaling, and TNF-? mRNA expression, as well as attenuates blood-brain barrier breakdown in a mouse model of diabetic retinopathy induced by streptozotocin (STZ; Item No. 13104).{57438}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]-phenol
  • Correlated keywords
    • NSC613744 Dendrobium H 460 1299 NFkB TNF? messanger m-RNA
  • Product Overview:
    Erianin is a benzoyl compound that has been found in D. chrysotoxum and has diverse biological activities.{57436,57437,57438} It inhibits the growth of H460 and H1299 lung cancer cells in a calcium/calmodulin-dependent manner, an effect that can be reversed by the ferroptosis inhibitor liproxstatin-1 (Item No. 17730) or ferrostatin-1 (Item No. 17729).{57436} Erianin (100 mg/kg) reduces tumor volume in an H460 mouse xenograft model. It increases colon length and body weight, as well as decreases colonic inflammation and the number of colonic ulcers in a mouse model of ulcerative colitis induced by dextran sulfate (DSS; Item No. 23250).{57437} Erianin (10 mg/kg) decreases retinal microglia accumulation, NF-kB signaling, and TNF-? mRNA expression, as well as attenuates blood-brain barrier breakdown in a mouse model of diabetic retinopathy induced by streptozotocin (STZ; Item No. 13104).{57438}

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