<em>ent</em>-<wbr/>8-<wbr/><em>iso</em>-<wbr/>15(S)-<wbr/>Prostaglandin F<sub>2?</sub>

ent–8-iso–15(S)-Prostaglandin F2?

CAT N°: 10010380
Price:

From 180.00 153.00

Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2? (ent-8-iso-15(S)-PGF2?) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively.{14005} This isoprostane is about ten-fold more potent than 8-iso-PGF2? in a whole blood platelet aggregation inhibition assay.{14928}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9?,11?,15S-trihydroxy-(12?)-prosta-5Z,13E-dien-1-oic acid
  • Correlated keywords
    • inhibitors inhibits inhibition 8-iso-PGF2.alpha. vasoconstriction platelet aggregation oxidative stress isoprostanes 15-F2t-isoprostane prostaglandins
  • Product Overview:
    Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2? (ent-8-iso-15(S)-PGF2?) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively.{14005} This isoprostane is about ten-fold more potent than 8-iso-PGF2? in a whole blood platelet aggregation inhibition assay.{14928}

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