Edonerpic (maleate)

Edonerpic (maleate)

CAT N°: 36026
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134.00 113.90

Edonerpic is a neurotrophic agent.{57910} It protects against sodium nitroprusside-induced mitochondrial dysfunction and apoptosis in primary rat cortical neurons when used at concentrations of 0.1 and 1 µM. Edonerpic (8.4 mg/kg per day, p.o.) prevents granule cell loss induced by amyloid-? (1-40) (A?40) and improves performance in the distance movement, random reward place search, and place learning tasks in rats.{57911} It also increases hippocampal neurogenesis and ameliorates A?40-induced spatial learning impairments in a rat model of Alzheimer’s disease.{57912}

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