DSP-4

DSP-4

CAT N°: 20707
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From 37.00 31.45

DSP-4 is an alkylating agent and a noradrenergic neurotoxin that inhibits the uptake of norepinephrine in rat cortical homogenates.{39935} It reduces dopamine-?-hydroxylase activity in rat brain and selectively depletes norepinephrine in rat cortex and locus coeruleus over the ventral forebrain, hypothalamus, and periphery.{39936,39935} DSP-4 (50 mg/kg) impairs tactile learning in the novel object recognition task in rats.{39937} It also decreases exploration in a novel open area and neophilia in a complex exploration test in rats.{39938}

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