Drospirenone-<wbr/><sup>13</sup>C<sub>3</sub>

Drospirenone-13C3

CAT N°: 34008
Price:

From 286.00 243.10

Drospirenone-13C3 is intended for use as an internal standard for the quantification of drospirenone (Item No. 23347) by GC- or LC-MS. Drospirenone is a synthetic progestogen.{41140} In vivo, drospirenone inhibits spontaneous ovulation in rats (ID50s = 0.3-1.0 mg/day) when administered orally or subcutaneously.{41141} Drospirenone (0.5 mg/animal) administered six times per day maintains pregnancy in ovariectomized pregnant rats. It reduces serum testosterone and luteinizing hormone (LH) in cynomolgus monkeys in a dose-dependent manner. Drospirenone (10 mg/animal per day) also inhibits testosterone-induced growth of the seminal vesicles and prostate in castrated rats. Formulations containing drospirenone have been used as oral contraceptives.{41142}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR,8dR,9aR)-4a,6a-dimethyl-3′,4,4a,4b,4′,5,6,6a,7a,8,8a,8b,8c,8d,9,9a-hexadecahydro-5’H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthrene-7,2′-furan]-2,5′(3H)-dione-3′,4′,5′-13C3
  • Correlated keywords
    • ZK30595 1,2-dihydroSpirorenone GCMS LCMS isotope
  • Product Overview:
    Drospirenone-13C3 is intended for use as an internal standard for the quantification of drospirenone (Item No. 23347) by GC- or LC-MS. Drospirenone is a synthetic progestogen.{41140} In vivo, drospirenone inhibits spontaneous ovulation in rats (ID50s = 0.3-1.0 mg/day) when administered orally or subcutaneously.{41141} Drospirenone (0.5 mg/animal) administered six times per day maintains pregnancy in ovariectomized pregnant rats. It reduces serum testosterone and luteinizing hormone (LH) in cynomolgus monkeys in a dose-dependent manner. Drospirenone (10 mg/animal per day) also inhibits testosterone-induced growth of the seminal vesicles and prostate in castrated rats. Formulations containing drospirenone have been used as oral contraceptives.{41142}

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