Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
€818.00
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€66.00 €56.10
€66.00 €56.10
Dronedarone is an antiarrhythmic agent and a derivative of amiodarone (Item No. 15213).{41032,41033} It inhibits muscarinic acetylcholine receptor-dependent potassium currents induced by carbachol (carbamoylcholine; Item No. 14486) or intracellular loading of GTP?S in single cells isolated from guinea pig atria (IC50s = 0.1 and 1 µM, respectively).{41033} Dronedarone (50 and 100 mg/kg) reduces sinus frequency and prolongs action potential duration (APD) in isolated rabbit ventricular myocardium. It increases atrial APD and the atrial effective refractory period (AERP) in a dog model of atrial fibrillation induced by rapid right atrial pacing.{57286} Formulations containing dronedarone have been used in the treatment of atrial fibrillation.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 100 mg, 250 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 141625-93-6 |
| Molecular formula | C31H44N2O5S • HCl |
| Smiles | CCCCC1=C(C(C2=CC=C(OCCCN(CCCC)CCCC)C=C2)=O)C3=CC(NS(C)(=O)=O)=CC=C3O1.Cl |
| Molecular weight | 593,2 |
| Custom code | 2935.90 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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