DLin-KC2-DMA

DLin-KC2-DMA

CAT N°: 34363
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From 83.00 70.55

DLin-KC2-DMA is an ionizable amino lipid (apparent pKa = 6.7) that has been used in combination with other lipids in the formation of lipid nanoparticles.{62187} Administration of Factor VII siRNA in DLin-KC2-DMA-containing LNPs reduces serum Factor VII protein levels in mice. LNPs containing DLin-KC2-DMA and androgen receptor siRNA decrease serum prostate-specific antigen (PSA) and tumor androgen receptor protein levels in an LNCaP mouse xenograft model.{62188}

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