DL-?-Difluoro<wbr/>methyl<wbr/>ornithine (hydro<wbr/>chloride hydrate)

DL-?-Difluoromethylornithine (hydrochloride hydrate)

CAT N°: 16889
Price:

From 48.00 40.80

DL-?-Difluoromethylornithine (DFMO) is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis.{27553} DFMO displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways.{27553,27552,27554,27555} Through inhibition of polyamine synthesis, DFMO also demonstrates antiparasitic activity in a model of C. parvum infection.{26876}

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