Cayman offers a full set of research tools to study citrullination, the post-translational protein modification linked to numerous inflammatory and autoimmune disorders.

While citrullination is most known for its contribution to these pathological processes, it also plays an important role in several physiological functions, including gene regulation and the formation of neutrophil extracellular traps (NETs) in response to immune challenge. We offer a diverse portfolio of research tools for the detection of citrullination and to explore the function of peptidylarginine deiminases (PADs), the catalysts of citrullination, which may hold promise as a therapeutic target.

Quantification of NET Formation Using an ELISA Specific to view the methods and data used to develop this kit.