24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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Dimethoate is an organophosphate pesticide.{42384} It is acaricidal against Kanzawa spider mites (LC50 = 7 ppm in an aqueous suspension) and inhibits purified Kanzawa spider mite acetylcholinesterase (AChE; IC50 = 3.3-5.2 nM). Dimethoate (50-200 ?M) reduces motility and viability and induces abnormal morphology of rat sperm.{42385} It also increases production of malondialdehyde (MDA) and reduces superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (Gpx) activities in rat epididymal sperm. In vivo, dimethoate (28 mg/kg per day) decreases sperm count, motility, and viability and increases the percentage of morphologically abnormal sperm in rats.{42386} Dimethoate also induces formation of carcinomas in the adrenal, thyroid, and pituitary glands of male and female rats as well as testicular atrophy, chronic renal disease, polyarteritis, and parathyroid hyperplasia in male rats.{42387}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 60-51-5 |
| Molecular formula | C5H12NO3PS2 |
| Smiles | CNC(CSP(OC)(OC)=S)=O |
| Molecular weight | 229,3 |
| Custom code | 2930.90 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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