Dichlorvos-d<sub>6</sub>

Dichlorvos-d6

CAT N°: 34517
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From 193.00 164.05

Dichlorvos-d6 is intended for use as an internal standard for the quantification of dichlorvos (Item No. 23727) by GC- or LC-MS. Dichlorvos is an organophosphate insecticide and inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 269 and 44 nM, respectively).{38709} It also binds to the M2 muscarinic receptor in rat heart homogenates.{38710} Dichlorvos is lethal to 4-week old German cockroach (B. germanica) nymphs (LD50 = 0.108 ?g per insect) and silkworms (B. mori) in third instar (LC50 = 6.63 mg/L) after 24 hours.{38711,38712} It is lethal to zebrafish (D. rerio) embryos (LC50 = 39.75 mg/L after 24 hours) and decreases swimming activity of larvae 6 days after fertilization when administered at a concentration of 25 mg/L in tank water.{38713} Dichlorvos (150 ppm for 80 weeks) also increases the incidence of benign and malignant neoplasms in male rats from 47 to 88% as compared to controls.{38714}

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