diacetoxy Scirpenol

diacetoxy Scirpenol

CAT N°: 11427
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diacetoxy Scirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases.{20564} It is toxic to fungi, plants, animals, and various mammalian cell cultures, inhibiting de novo protein synthesis.{20563} In a biological activity assay, DAS was shown to inhibit expression of the Arabidopsis MAMP-responsive reporter gene WRKY29p::GUS with an IC50 value of 50 nM, thereby suppressing a rapid cell death immune response important for plant defense.{20565}

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