Deslorelin (acetate)

Deslorelin (acetate)

CAT N°: 34041
Price:

From 165.00 140.25

Deslorelin is a peptide agonist of gonadotropin-releasing hormone (GnRH).{36464} It binds to the GnRH receptor (GnRHR) with a Ki value of 0.1 nM. Deslorelin decreases testicular volume, semen volume, sperm motility, and total sperm count, as well as increases the percentage of abnormal sperm, in dogs when administered via a subcutaneous implant at doses of 3, 6, and 12 mg/kg.{63143} It decreases disease severity and plasma levels of estradiol, 17-hydroxyprogesterone, and androstenedione in ferrets with adrenocortical disease (ACD) when administered at doses ranging from 3 to 4.41 mg/kg per implant.{63144} Deslorelin (4.7 mg/implant per animal) suppresses ovulation and estrus in cats.{63145} Formulations containing deslorelin have been used in the management of ACD in ferrets and ovulation regulation and artificial insemination in horses.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6-D-tryptophan-9-(N-ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), acetate
  • Correlated keywords
    • 67190-19-6 57773-65-6 hydroxy progesterone Ovuplant Suprelorin
  • Product Overview:
    Deslorelin is a peptide agonist of gonadotropin-releasing hormone (GnRH).{36464} It binds to the GnRH receptor (GnRHR) with a Ki value of 0.1 nM. Deslorelin decreases testicular volume, semen volume, sperm motility, and total sperm count, as well as increases the percentage of abnormal sperm, in dogs when administered via a subcutaneous implant at doses of 3, 6, and 12 mg/kg.{63143} It decreases disease severity and plasma levels of estradiol, 17-hydroxyprogesterone, and androstenedione in ferrets with adrenocortical disease (ACD) when administered at doses ranging from 3 to 4.41 mg/kg per implant.{63144} Deslorelin (4.7 mg/implant per animal) suppresses ovulation and estrus in cats.{63145} Formulations containing deslorelin have been used in the management of ACD in ferrets and ovulation regulation and artificial insemination in horses.

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