Demethylasterriquinone B1

Demethylasterriquinone B1

CAT N°: 21026
Price:

From 102.00 86.70

Demethylasterriquinone B1 (DMAQ B1) is a natural insulin mimic that activates insulin receptor tyrosine kinase (IRTK; EC50 = 6 µM).{33106,33107,33108,33109} It less potently activates IGF1R and EGFR (EC50s = 100 µM for both). DMAQ B1 induces glucose uptake in adipocytes and skeletal muscle cells without activating proliferation. DMAQ B1 binds GAPDH in vitro.{33105}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-[2-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]-2,5-cyclohexadiene-1,4-dione
  • Correlated keywords
    • insulin receptor tyrosine kinase mimic IRTK IGF1R EGFR DMAQB1 GAPDH adipocytes L783281 783281 783 281
  • Product Overview:
    Demethylasterriquinone B1 (DMAQ B1) is a natural insulin mimic that activates insulin receptor tyrosine kinase (IRTK; EC50 = 6 µM).{33106,33107,33108,33109} It less potently activates IGF1R and EGFR (EC50s = 100 µM for both). DMAQ B1 induces glucose uptake in adipocytes and skeletal muscle cells without activating proliferation. DMAQ B1 binds GAPDH in vitro.{33105}

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