Deferoxamine (mesylate)

Deferoxamine (mesylate)

CAT N°: 14595
Price:

From 109.00 92.65

Deferoxamine is a bacterial siderophore that chelates iron.{23098} It is used to experimentally inhibit iron-dependent prolyl hydroxylases (EC50 = 17.8 µM), thus preventing the degradation of isoforms of hypoxia inducible factor during normoxia.{23099,8840,23097} Deferoxamine has applications in diseases that are characterized by high levels of circulating iron, such as thalassemia major.{23096}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxy-butanediamide, monomethanesulfonate
  • Correlated keywords
    • 5115-09-3 17688-38-9 35908-62-4 70-51-9 natural products hypoxia desferrioxamine desferoxamine desferroxamine bacterial bacteria siderophore mesylate chelates irons inhibitors inhibits inhibitions prolyl hydroxylases iron-dependents dependents prevents preventions preventing degradations isoforms HIF hypoxia inducible factors normoxia thalassemia major B methanesulfonate desferal Ba33112 Ba-33112 NSC644468 NSC-644468 ferroptosis
  • Product Overview:
    Deferoxamine is a bacterial siderophore that chelates iron.{23098} It is used to experimentally inhibit iron-dependent prolyl hydroxylases (EC50 = 17.8 µM), thus preventing the degradation of isoforms of hypoxia inducible factor during normoxia.{23099,8840,23097} Deferoxamine has applications in diseases that are characterized by high levels of circulating iron, such as thalassemia major.{23096}

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