Deferitrin

Deferitrin

CAT N°: 33328
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From 501.00 425.85

Deferitrin is an iron chelator and a derivative of desferrithiocin that binds iron in a 2:1 (ligand:iron) ratio.{69152,69153} It inhibits the proliferation of L1210 murine leukemia cells (IC50 = 17 µM).{69154} Deferitrin (150 µmol/kg) induces iron excretion in iron-overloaded C. apella monkeys and beagle dogs with an iron clearing efficiency (ICE) of 14.5 and 9.3%, respectively.{69153} It reduces fecal and urine iron levels by 607 and 357 µg/kg in C. apella monkeys and beagle dogs, respectively.

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