Deethyl<wbr/>indanomycin

Deethylindanomycin

CAT N°: 28089
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From 420.00 357.00

Deethylindanomycin is a polyether antibiotic that has been found in S. setonii.{47369,47370} It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 µg/ml, respectively).{47370} It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 µg/g in the diet. Deethylindanomycin acts as an ionophore in lipid bilayer membranes and is more selective for potassium ions than calcium, magnesium, and sodium ions.{47369} It induces histamine release from rodent mast cells and human basophils in vitro in a calcium-dependent manner.

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