Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
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From €351.00 €298.35
Danicamtiv is a cardiac-specific myosin activator.{69039,69040} It activates human cardiac S1 myosin when used at a concentration of 3 µM but does not activate skeletal or smooth muscle myosin.{69039} It increases sarcomere activity of isolated porcine left ventricular and atrial myofibrils with 50% active concentration values (AC50s) of 6 and 3.6 µM, respectively. Danicamtiv (3 µM) increases calcium sensitivity of isolated porcine skinned left ventricular and atrial fibers. Danicamtiv (2-3 mg/kg) also prolongs systolic ejection time and improves left ventricular ejection fraction and stroke volume in a dog model of heart failure.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 100 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 1970972-74-7 |
| Molecular formula | C16H20F3N5O4S |
| Smiles | C[C@](F)(C1CCN(CC1)C(NC2=NOC=C2)=O)S(=O)(C3=CN(C)N=C3C(F)F)=O |
| Molecular weight | 435,4 |
| Custom code | 2933.39 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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ISO/IEC 17025:2005
ISO Guide 34:2009
Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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