Cysteamine (hydro<wbr/>chloride)

Cysteamine (hydrochloride)

CAT N°: 22193
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Cysteamine is a stable aminothiol with radioprotective activities.{41003} It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner.{41003,41004} Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects.{41004} In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts.{41005} Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans.{41006}

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