Territorial Availability: Available through Bertin Technologies only in France
- Synonyms
- 3-(2,2-dichloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, cyano(4-fluoro-3-phenoxyphenyl)methyl ester
- Correlated keywords
- 80850-08-4 83855-46-3 85782-82-7 BAY-FCR BAYFCR-1272 BAYFCR1272 BAY-Vl 1704 BAYVI BAYVI1704 Baythroid Cyfloxylate Eulan SP FCR1272 Optem PT 600 PT600 Preventol HS 12 HS12 Renounce Solfac 050EW Tempo 2 20WP 20 WP Tombstone Helios Aphytis Quince monitor Gonatocerus Encarsia Eretmocerus Whitefly Apis Aquilaria
- Product Overview:
Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).{36375,41867} It slowly activates rat recombinant Nav1.8 channels, delays inactivation by longer than 40 ms, and induces persistent tail currents in channels expressed in X. laevis oocytes.{36375} It also decreases the mean burst rate in rat primary neurons (IC50 = 0.99 ?M, respectively).{41867} Cyfluthrin is toxic to various insects, including A. melinus, G. ashmeadi, E. eremicus, and E. formosa (LC50s = 7, 67, 96, and 63 ng/ml, respectively) and the A. sinensis mosquito (LC50 = 0.446 ppm).{41868,41869} It is also toxic to A. mellifera honeybees (LD50 = 0.22 ppm), affecting locomotor activity and wing fanning behavior with an increase in the mean bout duration of time spent upside down, indicating disruption of the righting reflex, and a decrease in wing fanning behavior when administered at a dose of 10 ng/bee.{41870} Formulations containing cyfluthrin have been used for the control of insects in agriculture and for non-commercial purposes.
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.
Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009
Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.