Cyclopiazonic Acid-<sup>13</sup>C<sub>20</sub>

Cyclopiazonic Acid-13C20

CAT N°: 31297

Cyclopiazonic acid-13C20 is intended for use as an internal standard for the quantification of cyclopiazonic acid (Item No. 11326) by GC- or LC-MS. Cyclopiazonic acid is a mycotoxin that has been found in Penicillium and Aspergillus and an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA; IC50 = 0.6 µM).{20510,20511} In vivo, cyclopiazonic acid (11-14 mg/kg) induces ptosis, hypothermia, tremor, and cachexia, as well as induces lethality (LD50 = 13 mg/kg), in rats.{61119} It induces tachycardia and sedation in rabbits when administered at a dose of 10 mg/kg.

Territorial Availability: Available through Bertin Technologies only in France

Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.

Special Advice: Please check regulation status before ordering; additionel fees can apply.

  • Synonyms
    • (6aR,11aS,11bR)-10-(acetyl-13C2)-11-hydroxy-7,7-di(methyl-13C)-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1′,2′:2,3]isoindolo[4,5,6-cd]indol-9-one-1,2a,2a1,3,4,5,5a,6,6a,7,9,10,11,11a,11b,11c-13C16
  • Correlated keywords
    • GCMS LCMS myco toxin sarco endo plasmic cyclo piazonic hypo thermia tachy cardia CPA13C20
  • Product Overview:
    Cyclopiazonic acid-13C20 is intended for use as an internal standard for the quantification of cyclopiazonic acid (Item No. 11326) by GC- or LC-MS. Cyclopiazonic acid is a mycotoxin that has been found in Penicillium and Aspergillus and an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA; IC50 = 0.6 µM).{20510,20511} In vivo, cyclopiazonic acid (11-14 mg/kg) induces ptosis, hypothermia, tremor, and cachexia, as well as induces lethality (LD50 = 13 mg/kg), in rats.{61119} It induces tachycardia and sedation in rabbits when administered at a dose of 10 mg/kg.

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