CVT-313

CVT-313

CAT N°: 21044
Price:

From 94.00 79.90

CVT-313 is a competitive inhibitor of cyclin-dependent kinase 2 (Cdk2; IC50 = 0.5 µM in vitro).{32889} It displays 8.5- and 430-fold selectivity for Cdk2 over Cdk1 and Cdk4, respectively, and has no effect on other unrelated ATP-dependent serine/threonine kinases.{32889} CVT-313 induces cell cycle arrest at the G1/S boundary.{32889} CVT-313 is often used as a selective Cdk2 inhibitor, although at some concentrations and in some cells it may also inhibit Cdk1.{32889,32888,32890,23163}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2,2′-[[6-[[(4-methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bis-ethanol
  • Correlated keywords
    • CVT313 NG26 NG-26 Cdk2 Cdk-2 cyclin-dependent kinase
  • Product Overview:
    CVT-313 is a competitive inhibitor of cyclin-dependent kinase 2 (Cdk2; IC50 = 0.5 µM in vitro).{32889} It displays 8.5- and 430-fold selectivity for Cdk2 over Cdk1 and Cdk4, respectively, and has no effect on other unrelated ATP-dependent serine/threonine kinases.{32889} CVT-313 induces cell cycle arrest at the G1/S boundary.{32889} CVT-313 is often used as a selective Cdk2 inhibitor, although at some concentrations and in some cells it may also inhibit Cdk1.{32889,32888,32890,23163}

We also advise you