TAF 10 Peptide
TAF 10 Peptide
TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity.{16903} One vial of this peptide...
€191.00
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From €94.00 €79.90
From €94.00 €79.90
Crebanine is an aporphine alkaloid that has been found in Stephania venosa and has diverse biological activities.{65397,65398,65399,65400,65401} It is an antagonist of ?7 nicotinic acetylcholine receptors (nAChRs; IC50 = 19.1 µM) and inhibits sodium currents (INa) in isolated guinea pig ventricular myocytes (IC50 = 283 µM).{65397,65398} Crebanine is active against the Gram-positive bacteria M. lysodeikticus, B. cereus, B. megaterium, B. subtilis, and S. aureus (MICs = 0.312, 0.213, 0.312, 0.312, and 0.312 g/L, respectively), as well as the plant pathogenic fungi C. kaki, G. haraeanum, P. oryzae, R. solani, and C. graminicola (EC50s = 111, 64.7, 18.9, 42.5, and 40.5 mg/L, respectively).{65399} It inhibits the LPS-induced production of TNF-?, IL-6, nitric oxide (NO), and prostaglandin E2 (PGE2; Item No. 14010) in RAW 264.7 macrophages when used at a concentration of 29.5 µM.{65400} Crebanine inhibits the proliferation of A549 lung, MDA-MB-231 and MCF-7 breast, and SKOV3 and Caov-3 ovarian cells and reduces TNF-? induced invasion and migration of A549 cells in a concentration-dependent manner.{65401} It prevents scopolamine-induced memory deficits in the Morris water maze in mice when administered at a dose of 25 mg/kg.{65397}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 25127-29-1 |
| Molecular formula | C20H21NO4 |
| Smiles | CN1[C@@]2([H])C3=C(CC1)C=C(OCO4)C4=C3C5=CC=C(OC)C(OC)=C5C2 |
| Molecular weight | 339,4 |
| Custom code | 2933.39 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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