CPTH2 (hydro<wbr>chloride)

CPTH2 (hydrochloride)

CAT N°: 12086
Price:

From 146.00 124.10

Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. CPTH2 inhibits the HAT activity of Gcn5 both in vitro and in vivo, reducing histone H3K14 acetylation at a concentration of 0.8 mM.{21587} It is a useful tool to study the impact of Gcn5-dependent acetylation in various biological systems and recently has been used to control the replication of human adenovirus.{21588}

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