COX Inhibitor Pack

CAT N°: 10186
Price:

€932.00 €792.20

The Cayman COX Inhibitor Pack contains a combination of frequently used cyclooxygenase (COX) inhibitors. Each kit contains aspirin, the archetype nonselective, irreversible COX inhibitor.{816} A series of COX-2 selective inhibitors are available in the COX-PAK, including NS-398, one of the first reported and most widely used.{1222} Another COX-2-selective inhibitor included is CAY10404, with nearly 500,000-fold COX-2 selectivity.{8944} The potent COX-1-selective inhibitor SC-560 is an example of a reversible, diaryl heterocycle COX-1 inhibitor with low nM activity.{7675} Also included is valeroyl salicylate, an irreversible alkylator of COX enzymes with some selectivity toward COX-1.{1284} Resveratrol is also included in the COX-PAK due to its complex activities, which include COX inhibition, peroxidase inhibition, antioxidant activity, and gene regulation.{6817,3491}

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • cyclooxygenases PGHS-2 inducible synthases prostaglandins CAY10404 SC-560 SC-58125 valeroyl saliylate NS-398 aspirin resveratrol APHS inhibitors inhibits inhibition SC560 SC58125 NS 398 COX-2 COX2 COX-1 COX1 PGHS2 PGHS-1 PGHS1 10186 70330 70655 10006120 10007692 valdecoxib licofelone packs
  • Product Overview:
    The Cayman COX Inhibitor Pack contains a combination of frequently used cyclooxygenase (COX) inhibitors. Each kit contains aspirin, the archetype nonselective, irreversible COX inhibitor.{816} A series of COX-2 selective inhibitors are available in the COX-PAK, including NS-398, one of the first reported and most widely used.{1222} Another COX-2-selective inhibitor included is CAY10404, with nearly 500,000-fold COX-2 selectivity.{8944} The potent COX-1-selective inhibitor SC-560 is an example of a reversible, diaryl heterocycle COX-1 inhibitor with low nM activity.{7675} Also included is valeroyl salicylate, an irreversible alkylator of COX enzymes with some selectivity toward COX-1.{1284} Resveratrol is also included in the COX-PAK due to its complex activities, which include COX inhibition, peroxidase inhibition, antioxidant activity, and gene regulation.{6817,3491}

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