24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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Costunolide is a sesquiterpene lactone that is found naturally in certain plant extracts and in alternative medicine oils. It reduces growth (EC50 = 3-35 ?M) and induces apoptosis in assorted cancer cell lines.{23610,23612,23613} Costunolide inhibits the activation of Akt (15 ?M) in endometriotic epithelial cells and STAT3 activation in THP-1 cells (EC50 = 10 ?M).{23611,23614} It also inhibits telomerase activity in NALM-6 cells.{23610}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 25 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 553-21-9 |
| Molecular formula | C15H20O2 |
| Smiles | C/C1=C[C@@H](OC(C2=C)=O)[C@H]2CC/C(C)=CCC1, C/C1=C[C@@H](OC(C2=C)=O)[C@H]2CC/C(C)=CCC1, C/C1=C[C@@H](OC(C2=C)=O)[C@H]2CC/C(C)=CCC1, C/C1=C[C@@H](OC(C2=C)=O)[C@H]2CC/C(C)=CCC1 |
| Molecular weight | 232,3 |
| Custom code | 2932.19 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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