Compound C108

Compound C108

CAT N°: 9002951
Price:

From 109.00 92.65

Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation.{34400} In a mouse xenograft model of breast cancer, compound C108 (1 µM for 24 hours) reduces the proportion of tumor-initiating cells approximately 10-fold compared with untreated cells. In MDA-MB-453 cells, and in the patient-derived xenograft cell line MAXF 401, it diminishes mammosphere formation.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-hydroxy-benzoic acid, 2-[1-(2-hydroxyphenyl)ethylidene]hydrazide
  • Correlated keywords
    • MAXF401 MDAMB G3BP-2 MDAMB453
  • Product Overview:
    Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation.{34400} In a mouse xenograft model of breast cancer, compound C108 (1 µM for 24 hours) reduces the proportion of tumor-initiating cells approximately 10-fold compared with untreated cells. In MDA-MB-453 cells, and in the patient-derived xenograft cell line MAXF 401, it diminishes mammosphere formation.

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