Coelenterazine h

Coelenterazine h

CAT N°: 16894
Price:

From 276.00 234.60

Coelenterazine (Item No. 16123) is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin.{22804} Coelenterazine can be used to reconstitute the aequorin complex both in vivo and in vitro, emitting blue light when bound to calcium ions. Coelenterazine h is a synthetic derivative of native coelenterazine that exhibits 16-fold higher luminescence intensity (emission maximum ~466 nm; half-total time of 0.6-1.2 sec) than native coelenterazine.{6107} Aequorin complexes reconstituted with coelenterazine h are reported to be more sensitive to calcium ions than those employing the native constituent, providing a useful indicator for small changes in Ca2+ concentrations.{27442}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6-(4-hydroxyphenyl)-2,8-bis(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one
  • Correlated keywords
    • synthetic analog bioluminescence aequorin complexes reconstitution calcium ions Ca2+ biochemical fluorescent probe intracellular signaling 50815-16-2 2-deoxycoelenterazine 2deoxycoelenterazine luciferin Renilla bioluminescent derivative reconstitute indicator small change concentration
  • Product Overview:
    Coelenterazine (Item No. 16123) is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin.{22804} Coelenterazine can be used to reconstitute the aequorin complex both in vivo and in vitro, emitting blue light when bound to calcium ions. Coelenterazine h is a synthetic derivative of native coelenterazine that exhibits 16-fold higher luminescence intensity (emission maximum ~466 nm; half-total time of 0.6-1.2 sec) than native coelenterazine.{6107} Aequorin complexes reconstituted with coelenterazine h are reported to be more sensitive to calcium ions than those employing the native constituent, providing a useful indicator for small changes in Ca2+ concentrations.{27442}

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