Clofibric Acid

Clofibric Acid

CAT N°: 21608
Price:

From 46.00 39.10

Clofibric acid is a peroxisome proliferator-activated receptor ? (PPAR?) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate (Item No. 10956).{54935} It is formed from clofibrate by tissue and serum esterases.{54936} Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats.{54937} It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 µg/L.{54938} Clofibric acid has been found in wastewater effluent.{54939}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-(4-chlorophenoxy)-2-methyl-propanoic acid
  • Correlated keywords
    • 60120-73-2 94592-92-4 Arteriohom clofibrinic CPIB CPIBA PCIB PCPIB Regadrin Regulipid Chlorfibrinic Chlorofibrinic Chlorophibrinic Clofibrate Clofibrilic Clofibrin NSC1149 2-(4-Chlorophenoxy)isobutyric 4-Chlorophenoxyisobutyric PPAR-? Cyprinus waste water
  • Product Overview:
    Clofibric acid is a peroxisome proliferator-activated receptor ? (PPAR?) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate (Item No. 10956).{54935} It is formed from clofibrate by tissue and serum esterases.{54936} Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats.{54937} It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 µg/L.{54938} Clofibric acid has been found in wastewater effluent.{54939}

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